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Opening NFL Week 2 Odds, Betting Lines, Picks & Predictions for This Week

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Week 1 of the NFL season came to a close last night in a thrilling New York Jets victory over the Buffalo Bills in overtime, where the Jets returned a punt for a game winning touchdown. Aaron Rodgers sadly endured a brutal achilles injury and will now be out for the rest of the season. The Bills vs. Jets matchup wasn’t the only game that ended in dramatic fashion, though, and it’s clear that we’re in for quite the season.

In this article, we’ll take a look at the Week 2 slate, NFL odds and early betting lines to make our opening NFL Week 2 picks. There are plenty of great matchups that we could have targeted in our NFL Week 2 predictions, and we’ll be hand picking a few games that we believe we can find an edge on. Keep reading for our NFL predictions for this week with NFL odds presented by Caesars Sportsbook.

NFL WEEK 2 PREDICTIONS & BEST BETS: Ravens +3.5 (-120), Patriots Money Line (+115) & Eagles -7 (-110 at Caesars Sportsbook)

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Opening NFL Odds, Lines & Spreads at Caesars Sportsbook for Week 2

Before we detail our NFL predictions for this week, first, we’ll be listing all of the NFL betting odds and NFL betting lines available to us at Caesars Sportsbook for Week 2. These will include the money line, spreads and game totals for every game.

  • Vikings (+260) vs. Eagles (-335)
    • Spread: Vikings -7 (-110) vs. Eagles +7 (-110)
    • Total: Over 48.5 (-110) vs. Under 48.5 (-110)
  • Chargers (-160) vs. Titans (+135)
    • Spread: Chargers -3 (-110) vs. Titans +3 (-110)
    • Total: Over 45.5 (-110) vs. Under 45.5 (-110)
  • Seahawks (+210) vs. Lions (-260)
    • Spread: Seahawks +6 (-110) vs. Lions -6 (-110)
    • Total: Over 48.5 (-110) vs. Under 48.5 (-110)
  • Chiefs (-160) vs. Jaguars (+135)
    • Spread: Chiefs -3 (-110) vs. Jaguars +3 (-110)
    • Total: Over 51 (-110) vs. Under 51 (-110)
  • Bears (+140) vs. Buccaneers (-165)
    • Spread: Bears +3 (-110) vs. Buccaneers -3 (-110)
    • Total: Over 41.5 (-110) vs. Under 41.5 (-110)
  • Ravens (+148) vs. Bengals (-175)
    • Spread: Ravens +3.5 (-120) vs. Bengals -3.5 (+100)
    • Total: Over 46.5 (-110) vs. Under 46.5 (-110)
  • Colts (-120) vs. Texans (+100)
    • Spread: Colts -1 (-110) vs. Texans +1 (-110)
    • Total: Over 40 (-110) vs. Under 40 (-110)
  • Packers (-120) vs. Falcons (+100)
    • Spread: Packers -1.5 (-110) vs. Falcons +1.5 (-110)
    • Total: Over 40.5 (-110) vs. Under 40.5 (-110)
  • Giants (-210) vs. Cardinals (+175)
    • Spread: Giants -4 (-110) vs. Cardinals +4 (-110)
    • Total: Over 39.5 (-110) vs. Under 39.5 (-110)
  • 49ers (-365) vs. Rams (+285)
    • Spread: 49ers -8 (-110) vs. Rams +8 (-110)
    • Total: Over 44.5 (-110) vs. Under 44.5 (-110)
  • Commanders (+158) vs. Broncos (-190)
    • Spread: Commanders +3.5 (-110) vs. Broncos -3.5 (-110)
    • Total: Over 39 (-110) vs. Under 39 (-110)
  • Dolphins (-135) vs. Patriots (+115)
    • Spread: Dolphins -2.5 (-110) vs. Patriots +2.5 (-110)
    • Total: Over 47.5 (-110) vs. Under 47.5 (-110)
  • Saints (-165) vs. Panthers (+140)
    • Spread: Saints -3 (-110) vs. Panthers +3 (-110)
    • Total: Over 40 (-110) vs. Under 40 (-110)
  • Browns (-130) vs. Steelers (+110)
    • Spread: Browns -2 (-110) vs. Steelers +2 (-110)
    • Total: Over 40 (-110) vs. Under 40 (-110)

Continue reading for a few of our best NFL picks this week and NFL predictions for this week, using these NFL odds via Caesars Sportsbook.

Opening NFL Week 2 Picks, NFL Predictions for This Week & Best NFL Bets This Week

After reviewing the NFL betting lines and NFL betting odds for Week 2, our experts have a few best NFL bets this week that we believe we can take advantage of. To start off, we really like the Ravens +3.5 (-120 at Caesars) this week against the Bengals. The Ravens looked sharp this past week in a big win, while the Bengals played a rough game.

Cincy will look to bounce back here, but it will be tough against a Ravens team run by Lamar Jackson who just won 25-9 and got a huge game out of rookie WR Zay Flowers. We’ll take the Ravens +3.5 here. It just seems like too many points and the Ravens should keep the game within a field goal or win outright against a Bengals team that may need some time to get it together.

Our next best bet for NFL Week 2 picks is the Patriots money line (+115 at Caesars). The Patriots went toe-to-toe with the defending NFC Champion Eagles last Sunday, and lost a heartbreaker in which they had multiple opportunities at game winning drives. The Patriots defense looked very sharp against Hurts and the Eagles, and the Dolphins aren’t as complete of a team as Philly. With home field advantage and a hungry team looking for its first win, let’s ride with the Patriots to come out on top this time in a close one against their division rival.

Lastly, to close out our NFL week 2 predictions, we love the Eagles -7 (-110 at Caesars) at home over the Vikings. The Vikings did not look very sharp in their loss to Tampa Bay last week, and they’ll travel to a hostile Philly environment to face an Eagles team who wasn’t on their A-game this past week. The Eagles will be looking for an offensive explosion against a Vikings defense that’s average at best. We like the Eagles to win this game by multiple scores in a potential blowout. Our experts are happy to lay the points on a -7 spread here for the Eagles.

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Notable NFL Scores: Week 1

Now that we’ve reviewed the NFL betting lines and NFL betting odds for our NFL picks this week, let’s look back at some of the noteworthy scores from Week 1. First off, the Browns beat the Bengals 24-3 in a dominant performance. The Browns looked great on both sides of the ball and were able to shut down Joe Burrow almost completely. Also, the Rams won in a big way, with a 30-13 victory over a good Seahawks team. Stafford is fully healthy again, and it feels like he’s flown under the radar after his Super Bowl win.

Finally, we believe the 49ers vs. Steelers score was noteworthy. Pittsburgh got destroyed at home 30-7 after having high hopes leading into this one. Is Kenny Pickett the real deal, and how good are the 49ers? These scores leave us excited to see what happens as the season continues, and we can’t wait to watch our NFL week 2 picks play out!

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