
NFL Week 16 Picks, Predictions, Odds & Betting Lines: This Week's Games
Week 15 of the NFL season is officially in the books, following a huge Seahawks upset over the Eagles on Monday Night Football. Backup quarterbacks continue to make their mark on the NFL this year, and it’s been a fun season. Now, we look ahead to week 16 as the regular season begins winding down and teams are making their final playoff push in the coming weeks. In this article, we take a look at some of our favorite NFL Week 16 picks, with odds provided by DraftKings Sportsbook.
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NFL WEEK 16 PICKS & PREDICTIONS: Eagles -11.5 (-110), Commanders +3 (-108) & Cowboys +1.5 (-110 at DraftKings Sportsbook)
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NFL Picks & Best Bets for Week 16 Focusing on Eagles -11.5 (-110 at DraftKings
On Christmas Day, the New York Giants travel to Philadelphia to square off against an Eagles team that has now lost three straight games after the tough Monday Night Football loss to the Seahawks. Jalen Hurts was under the weather and questionable to play going into the game. It was clear he was not 100%, as the Eagles punted five times in total and Hurts threw two crucial interceptions in the second half.
We expect the Eagles to respond in a huge way at home on Christmas against a much weaker Giants team. Tommy Devito’s beginner's magic appeared to be over this past week in a 24-6 loss to the Saints. Now they face a much better Eagles team who will be playing angrily. Our experts believe this spread should be at least -14 in favor of Philly, but the line is currently only Eagles -11.5 (-110 at DraftKings Sportsbook). This is absolutely the favorite of our NFL Week 16 picks, as we expect a good old-fashioned beatdown by the Eagles.
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Expert NFL Predictions for Week 16
In addition to our main pick of Eagles -11.5, we also want to add a couple more NFL Week 16 predictions that caught our eye. First, we want to take a look at the Commanders vs. Jets game. The Jets are an absolute mess at the moment, following a 30-0 loss to the Dolphins this past week. The quarterback position is a major issue for New York, and the Commanders are respectable on both sides of the ball.
Jacoby Brissett came in for Sam Howell late in the game to drive downfield for two touchdowns and almost make a wild comeback against the Rams in LA. Regardless of which QB gets the nod for the Commanders this week, we believe Washington will come to play against this decimated Jets squad. Let’s happily take the Commanders +3 (-108 at DraftKings), and expect the Jets' rough offensive performance to continue.
Lastly, to close out our NFL Week 16 picks, we side with another slight underdog. The Cowboys travel to Miami to face the Dolphins on Sunday. Dallas took a bit of a beatdown up in Buffalo on Sunday, and just like the Eagles, we think this is a great bounce-back spot for the Cowboys. The Dolphins are definitely a good match for Dallas and a potential Super Bowl matchup is in the air, but it feels like a possible let-down spot for Miami after winning 30-0 over a struggling Jets team. We think the Cowboys have enough offensive firepower to match the Dolphins, as well as a strong enough defensive front to pressure Tua, who’s throwing to a Tyreek Hill that may still be slightly banged up this week. To wrap up our NFL predictions this week, we’re rolling with Dallas to get a close win in Miami and cover +1.5 (-110 at DraftKings).
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NFL Odds & Betting Lines for Week 16
Below, we’ve listed all of the NFL odds this week, with all main market lines provided by DraftKings Sportsbook.
Saints vs. Rams
- Money Line: Saints (+170) vs. Rams (-210)
- Spread: Saints +4 (-110) vs. Rams -4 (-110)
- Total: Over 44.5 (-110) // Under 44.5 (-110)
Bengals vs. Steelers
- Money Line: Bengals (-130) vs. Steelers (+110)
- Spread: Bengals -2.5 (-110) vs. Steelers +2.5 (-110)
- Total: Over 37.5 (-110) // Under 37.5 (-110)
Bills vs. Chargers
- Money Line: Bills (-700) vs. Chargers (+500)
- Spread: Bills -10.5 (-115) vs. Chargers +10.5 (-105)
- Total: Over 42.5 (-110) // Under 42.5 (-110)
Packers vs. Panthers
- Money Line: Packers (-225) vs. Panthers (+185)
- Spread: Packers -5 (-110) vs. Panthers +5 (-110)
- Total: Over 37 (-110) // Under 37 (-110)
Lions vs. Vikings
- Money Line: Lions (-162) vs. Vikings (+136)
- Spread: Lions -3 (-110) vs. Vikings +3 (-110)
- Total: Over 47 (-110) // Under 47 (-110)
Colts vs. Falcons
- Money Line: Colts (-135) vs. Falcons (+114)
- Spread: Colts -2.5 (105) vs. Falcons +2.5 (-115)
- Total: Over 44 (-110) // Under 44 (-110)
Browns vs. Texans
- Money Line: Browns (+120) vs. Texans (-142)
- Spread: Browns +2.5 (-108) vs. Texans -2.5 (-112)
- Total: Over 42.5 (-110) // Under 42.5 (-110)
Commanders vs. Jets
- Money Line: Commanders (+130) vs. Jets (-155)
- Spread: Commanders +3 (-115) vs. Jets -3 (-105)
- Total: Over 38 (-108) // Under 38 (-112)
Jaguars vs. Buccaneers
- Money Line: Jaguars (-110) vs. Buccaneers (-110)
- Spread: Jaguars -1 (-105) vs. Buccaneers +1 (-115)
- Total: Over 43.5 (-110) // Under 43.5 (-110)
Cowboys vs. Dolphins
- Money Line: Cowboys (+102) vs. Dolphins (-122)
- Spread: Cowboys +1.5 (-110) vs. Dolphins -1.5 (-110)
- Total: Over 51.5 (-110) // Under 51.5 (-110)
Cardinals vs. Bears
- Money Line: Cardinals (+180) vs. Bears (-210)
- Spread: Cardinals +4 (-105) vs. Bears -4 (-112)
- Total: Over 44 (-108) // Under 44 (-112)
Patriots vs. Broncos
- Money Line: Patriots (+235) vs. Broncos (-290)
- Spread: Patriots +6.5 (-110) vs. Broncos -6.5 (-110)
- Total: Over 34 (-112) // Under 34 (-110)
Raiders vs. Chiefs
- Money Line: Raiders (+370) vs. Chiefs (-485)
- Spread: Raiders +10 (-115) vs. Chiefs -10 (-105)
- Total: Over 41.5 (-115) // Under 41.5 (-105)
Giants vs. Eagles
- Money Line: Giants (+440) vs. Eagles (-600)
- Spread: Giants +10.5 (-110) vs. Eagles -10.5 (-110)
- Total: Over 43 (-110) // Under 43 (-110)
Ravens vs. 49ers
- Money Line: Ravens (+195) vs. 49ers (-238)
- Spread: Ravens +5.5 (-110) vs. 49ers -5.5 (-110)
- Total: Over 46 (-110) // Under 46 (-110)
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NFL Power Rankings for Week 16
Before sending you on your way, we want to list our top 5 NFL power rankings heading into week 16. Our rankings are below.
- San Francisco 49ers
- Baltimore Ravens
- Miami Dolphins
- Philadelphia Eagles
- Buffalo Bills
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